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Biography

Shaun is a professor and joined the Centre in 2013 via a meandering path to health services research.  He trained as a physicist and then did a bioengineering PhD involving lasers, blood and bits of skin.  Then came health informatics, amputee rehabilitation and a move to Oslo, followed by eight years at the University of Dundee, three of which as Assistant Director of the Tayside Clinical Trials Unit.  He also has a guest professor post in the Department of Women's and Children’s Health at Uppsala University, Sweden.  

Shaun is active in the field of efficient trial design, particularly pragmatic trial design, improved recruitment and retention interventions for trials, the design of complex interventions and the effective presentation of research evidence. He led the development of the NIHR INCLUDE Ethnicity Framework (), a tool to help trialists design inclusive trials, PRO EDI (), a tool to help systematic reviewers consider equity in their reviews, and PRECIS-2 (), a tool to match trial design decisions to what the users of the results need, and the INFORM Structured Grant Form for Trials (), a new, evidence-based type of grant form for trials that is designed to improve the informativeness of funded trials. 

He leads an initiative called Trial Forge () that aims to be more systematic about how we identify, generate and use research evidence in making trial design, conduct, analysis and reporting decisions.

Best email for contact is streweek@mac.com.

External Memberships

Funding committees

• Panel member for the French Government Agence Nationale de la Recherche ‘Evaluation of new tools, new uses and new methodological approaches in clinical research’ funding program - 2025 - 2026.
• Chair, Health Improvement, Protection and Services Committee, Chief Scientist Office, 2017 - 2021. Deputy Chair 2012 - 2017.
• External member of the Health Research Board - Ireland Clinical Trial Network Renewals Panel 2020-2021.
• External member of the Scottish Cancer Foundation Doctoral Training Fellowship award Panel 2020.
• Rapporteur and panel member for the European Cooperation in Science and Technology (COST) Program 2019.
• External member of the Health Research Board - Ireland/Interreg Cross-border Healthcare Intervention Trials in Ireland Network (CHITIN) Panel 2018. 

Advisory and other committees (current)

• Chair, Steering Committee for NIHR funded study ‘Cavernous malformations of the brain: A Randomised Efficacy study of Aspirin versus placebo (CARE-Aspirin)', (2025 - present).
• Member, Policy and Research Committee (Scientific Advisor), Grampian Regional Equality Council (GREC), 2022- present.
• Member, Steering Committee for The People’s Review, University of Galway, 2022 - present.
• NCITA Prostate Cancer Global Trial Steering Committee, University College London, 2022 - present. 
• Scientific Advisor, Norwegian Centre for Epidemic Interventions Research, Oslo, Norway, 2021 - present.
• Chair, Trial planning subgroup of the NHS Research Scotland Restart Advisory Group ‘Data & Digital’ Working Group, 2021 - present.
• Member, Steering Committee for Ileostomy and Internal Pouch Association and Kingston Trust -funded study Hernia Active Living Trial (HALT), 2021 - present.
• Co-chair, MRC-NIHR Trial Methodology Research Partnership Inclusivity Subgroup, 2020 - present.
• Member, Scientific Advisory Committee NIHR Applied Research Collaboration (ARC) North East and North Cumbria, 2020 - present.
• Member, Advisory Group, NIHR-funded Research on Research Registry and Hub, 2020 - present.
• Chair, Steering Committee for NIHR funded study ‘Snacktivity’ to promote physical activity and reduce future risk of disease in the population (2019 – present).
• Member, International Advisory Board, Research Square (publisher), 2019 - 2022.

Publishing

• Editor-in-Chief for Trials (2018 - 2025).

Prizes and Awards

• Spinoza Guest Professorship and lecture series, April 19th to 23rd 2027, University Medical Centre Amsterdam.
• Trial Forge won the 2019 Cochrane-REWARD Prize for reducing research waste ()

Research Overview

Randomised trials; Trial methodology; Trial efficiency; Inclusion in trials; Recruitment; Retention; Communicating research.

A good place to look for seeing what I do is the Trial Forge website:

Current Research

Some of the projects I’m involved with include:

• Trial Forge ().  A systematic approach to improving trial efficiency.
• READI: improving the inclusiveness of trials across Europe ().
• EDICT: a Marie Sk艂odowska-Curie PhD network focused on improving equity, diversity and inclusion in trials ().
• INFORM: developing materials to give trials their best chance of being informative and useful during the pre-funding process ().
• SENSITISE: developing undergraduate and professional training materials to support inclusive trial design ().
• ActWELL: a lifestyle change trial involving women attending routine breast screening in Scotland ().
• STEER: Systematic Techniques to Enhance Retention in RCTs.  Developing theory-informed ways to reduce loss-to-follow-up in trials.
• Making clinical trials more efficient: consolidating, communicating and improving knowledge of patient recruitment interventions.
• The DECIDE project ().  Improving the way guidelines are presented to users.
• Making clinical trials more relevant: improving and validating the PRECIS tool for matching trial design decisions to trial purpose - see and.
• OPTIMISTIC - Observational Prolonged Trial In Myotonic dystrophy type 1 to Improve Stamina, a Target Identification Collaboration ()
• EuroFIT - improving men's health through healthy living programs delivered through football clubs ().
• The ECLS trial (): a trial evaluating the EarlyCDT-Lung blood test, which is designed to pick up lung cancer earlier, as part of a potential lung cancer screening program.
• The use of cardiac rehabilitation services to aid the recovery of colorectal cancer patients: A pilot randomised controlled trial (RCT) with embedded feasibility study - .
• Improving the normalisation of complex interventions: Developing quantitative measures for users based on Normalisation Process Theory ()
• Systematic Techniques for Assessing Recruitment to Trials (START): a programme to test recruitment interventions ()
• A web-based platform to support the development-evaluation-implementation process of the 2008 MRC framework for developing and evaluating complex interventions(see )
• Supporting the Use of Research Evidence (SURE) for Policy in African Health Systems (
• Football Fans in Training (FFIT): a randomized controlled trial of a gender-sensitive weight loss and healthy living programme delivered to men aged 35-60 by Scottish Premier League (SPL) football clubs (/)

Funding and Grants

Selected grants

June 2026 (2 years; start date under negotiation)

€195,761 awarded by HRB for a project called ‘Development and Validation of PRECIS-3-C: Extending the PRECIS-3 Tool for Cluster Randomised Trials’ to Willis A, Campbell M, Fretheim A, Shiely F, Taljaard M, Treweek S, Zwarenstein M. 

April 2025 (1/3/2026 - 28/2/30)

€4,349,934 awarded by the EU Horizon Programme for a Marie Sk艂odowska-Curie Action Doctoral Network to Morrissey E, Treweek S., Peters S, Boronia A, Puljak L, Boutron I. for a network called ‘Advancing Equity, Diversity, and Inclusion in Clinical Trials” (EDICT). S. Treweek (co-app and partner lead). 

June 2024 (1/1/2025 - 31/12/2030)

€67,968,110 (comprising €32,995,610 EU funding, remainder industry-matched funding) awarded by the EU Innovative Medicines Initiative (IMI) to a collaboration of 69 partners, 29 of which are pharmaceutical companies, led by A Borobia, HOSPITAL UNIVERSIATRIO LA PAZ, Spain for a project called ‘Research In Europe and Diversity Inclusion' (READI). S. Treweek (co-app and partner lead).

March 2024 (8/4/2024 - 31/12/2025)

$213,060 awarded by the Bill & Melinda Gates Foundation to Shaun Treweek (main applicant) for a project called ‘Improving pre-funding peer review to increase the informativeness of randomized trials.’

December 2023 (1/4/2024 - 30/9/2027)

£3,336,328 awarded by NIHR to Turvill J, Watson A, MacLennan G, Hudson J, Treweek S (co-app), McCormack, Atkin K, Varghese A, Dolwani S, Hurt C, Nixon L, Ballantine L, Rogers S for a project called ‘ColoCap: determining the diagnostic accuracy of colon capsule endoscopy compared to standard colonoscopy in patients at risk of colorectal disease’. 

November 2023 (1/12/2023 - 30/11/2026)

€400,000 awarded by EU ERASMUS+ to Shiely F, Kubiak C, Rychlí膷ková J, Treweek S (co-app and partner lead) for a project called ‘incluSivE cliNical trialS: traIning and educaTion to increase Involvement of under-SErved groups’.

November 2023 (1/4/2024 - 31/3/2028)

£2,389,056 awarded by NIHR to Kolehmainen N, Armitage S, MacLennan G, McNuff J, Rapley T, Vale L, Bray Nathan, Treweek S (co-app), Morris C, Marshall J, Allen C, Pennington L, Parr J, Robinson T, Sutton R for a project called ‘Health Technology Assessment (HTA) Project: NIHR156487: Investigating the clinical and cost- effectiveness of CHildren’s Early Self-care Support in children with neurodisability: the CHESS cluster randomised controlled trial’.

January 2023 (1/4/2023 - 31/3/2027)

£315,708 awarded by NIHR to Boxall C for a PhD Fellowship with supervisors Bradbury K, Alwan N, Griffiths G, Treweek S (co-app and supervisor) for a project called ‘Barriers and facilitators to initial participation and ongoing engagement in research using digital trial methods: A qualitative exploration from diverse populations’.

December 2022 (1/6/2023 - 31/12/2024)

£149,368 awarded by NIHR to Stuart B, Sunga R, Newton S, Eldridge S, Sohanpal R, Treweek S(co-app), Abdur R. for a project called ‘Better collaboration for better health: building trustworthy and sustained collaboration with diverse ethnic communities to improve equity and health outcomes’.

November 2022 (1/6/2023 - 31/5/2024)

£99,862 awarded by NIHR to MacLennan S, Bekheit M, Watson V, Maclennan G, Treweek S(co-app), van Hemelrijck M, Murchie P, Hebditch V, Sunga R. for a project called ‘ICANEQUAL: Reducing inequalities for those at risk and those diagnosed with Hepatocellular Carcinoma (HCC)’.

July 2022 (1/10/2022 - 30/9/2025)

531,674 CAD awarded by the Canadian Institutes of Health Research to Weijer, C, Taljaard M, Althabe F,  Binik A, Brehaut J, Eldridge S, Ferrand R, Gillies K, Giraudeau B, Goldstein C, Grimshaw J, Hemkens L, Hemming K, Johri, Kim S, Largent E, Leese J, London A, Magwood O, Marlin S, Mbuagbaw L, Mitchell S, Nicholls S, Petkovic J, Treweek S, Tugwell P, Welch V, van der Graaf R. for a project called ‘Ethical issues in cluster randomized trials: using stakeholder and patient engagement to generate guidance for the ethical design and conduct of trials evaluating clinical, health policy, health systems, and public health interventions.’ 

July 2022 (1/4/2023 - 31/3/27)

€370,000 awarded by Health Research Board to Shiely F, Loudon K, Nichol A, Taljaard M, Treweek S, Zwarenstein M for a study called ‘Development, validation and dissemination of the PRECIS-3 tool to support the design of pragmatic randomised controlled trials: Towards making clinical trials part of routine clinical care.’

April 2022 

£11,985 awarded by the NHS Grampian Endowment Fund to Gardner H, Treweek S, Wilson P, Thompson L, Rodgers, N, Murray C. for a study called ‘A qualitative interview study with adults living in remote and rural areas of Grampian to explore barriers and facilitators to participation in clinical trials.’

March 2022 

£1,625,150 awarded by NIHR to Parker A, Treweek S, Clarke M, Grimshaw J, Torgerson D for a project called ‘Using implementation science and Studies Within A Trial (IMPLEMENT SWATs) to improve evidence-based participant recruitment and retention in randomised controlled trials.’

January 2022 

AUS$149,402 awarded by the Australian National Health and Medical Research Council to Brijnath B, Gardner H, Ghersi D, Treweek S, Chan A-W, Orkin A, Welch V,     Owusu-Addo E, Nkrumah K. for a study called ‘Proposal for guidelines to improve the planning and reporting of variables related to ethnic diversity in RCTs, as an extension of the Standard Protocol Items: Recommendations for Interventional Trials.’