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The School of Biological Sciences

Dr Sharon Mitchell

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Dr Sharon Mitchell
Dr Sharon Mitchell
Dr Sharon Mitchell

PhD (Aberdeen University 2002)

Advanced Research Fellow

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Email Address
s.e.mitchell@abdn.ac.uk
Office Address

319, Zoology Building, Tillydrone Avenue, Aberdeen, AB24 2TZ

School/Department
School of Biological Sciences




Biography

2015-date       Advanced Research Fellow, Lab Manager Energetics Research Group

Research

Supervision

2016-2022 Megan Simpson "The impact of reproduction on physiology and oxidative stress in female C57BL/6 mice"

2016-2020 Jazmin Mendoza “Impacts of the thermic effect of food on feeding behaviour in mice: a test of the heat dissipation limits theory”

2015-2020 Emem Udoh PhD “Impacts of Calorie Restriction on Behaviour and Post-restriction Hyperphagia”

2015-2017 Heba Althubaiti “Fruit and Vegetable Intake and its Relationship with Health Parameters in Primary School Children”

Masters

2021-2022 Master of Science by Research Daniel Phillips “Bioinformatic Characterisation of Alternative Splicing in Three Different Tissues of Male C57BL/6 Mice Following Short-Term Graded Calorie Restriction"

2019-2020  MSci Daniel Phillips “Remodelling of three different tissues in the male C57BL/6 mouse during short-term graded caloric restriction is caused by tissue-specific variations in cell size and number”

2018-2019  MRes Stephanie Summers "The Impact of Short-Term Graded Calorie Restriction on Melanocortin-3 receptor (MC3R) Knockout Mice"

2013-2015 MSci  Megan Simpson “The effect of maternal age on offspring susceptibility to high fat diet induced obesity and offspring expression of hypothalamic obesity related genes”.

2011-2013 MRes Dawn Graham, “The Role of Neuropeptides and their Receptors in Response to Increased Hunger, Reduced Food Intake and Reduced Body Fat Content”.

2011-2013 MRes Nicole Culbert, “Does Hunger Neuropeptide and Energy Balance Manipulation Affect Metabolic Rate and Antioxidant Activity in C57BL/6 Mice under Caloric Restriction?”

Supervisor of a number of Erasmus Funded Internships from AgroSup, Djon, France.

Teaching

Courses

Teaching Responsibilities

Lab Skills in Biosciences (BI35F4), co-coordinator with Cath Jones

Supervisor for laboratory-based research projects for Honours students

 

Lecturer on following courses:

Comparative Physiology 2 (BI3512)

Diversity of Life 2 (BI1512)

Publications

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  • The susceptibility to weight gain in male C57BL/6 mice fed high-fat diet is due to a small set of genes predominantly not expressed in the brain

    Wu, Y., Rudolf, A. M., Wang, L., Zhang, Z., Niu, C., Xia, F., Li, M., Wang, A., Derous, D., Mitchell, S. E., Zhang, H., He, Y., Speakman, J. R.
    Proceedings of the National Academy of Sciences, vol. 123, no. 43, pp. e2613656123
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Deuterium between 31 and 1021鈥痯pm in dietary water has no effect on lifespan in the adult housefly (Musca domestica)

    Riddle, A., Hinson, C., Thomson, P., Hambly, C., Morimoto, J., Speakman, J. R., Mitchell, S. E.
    Journal of Insect Physiology, vol. 175, 105078
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction

    Phillips, D., Mitchell, S., Derous, D., Speakman, J.
    Life metabolism, vol. 5, no. 2, loaf046
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

    Moulds, T. P., Mitchell, S. E., Yang, X., Guo, W., Chen, E., Adams, P. D., Speakman, J. R.
    Aging Cell, vol. 25, no. 1, e70342
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Effects of graded calorie restriction: XXII. Impact of long-term graded calorie restriction on tissue partitioning, digestive efficiency, bone health, and coordination in male C57BL/6J mice

    Mitchell, S., Heib, L., Green, C. L., Derous, D., Hambly, C., Speakman, J.
    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 80, no. 11, glaf168
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory

    Mitchell, S. E., Simpson, M., Coulet, L., Gouedard, S., Hambly, C., Morimoto, J., Allison, D. B., Speakman, J. R.
    Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 42, e2408682121
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake

    Smith, D. L., Mitchell, S. E., Johnson, M. S., Gibbs, V. K., Dickinson, S., Henschel, B., Li, R., Kaiser, K. A., Chusyd, D. E., Brown, A. W., Allison, D. B., Speakman, J. R., Nagy, T. R.
    GeroScience, vol. 46, pp. 4809鈥�4826
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Not feeling the heat?: Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature.

    Osorio Mendoza, J., Mitchell, S., Hambly, C., Allison, D. B., Speakman, J.
    Appetite, vol. 200, 107421
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction

    Gutierrez, E., Mitchell, S., Hambly, C., Sayle, K. l., Von kriegsheim, A., Speakman, J. r., Britton, K.
    iScience, vol. 27, no. 6, 110059
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Turmeric shortens lifespan in houseflies

    Laurie, S., Ainslie, L., Mitchell, S., Morimoto, J.
    Frontiers in Insect Science, vol. 4, 1376011
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
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