BSc (Hons), MLitt, PhD
Head of Trial Management
- 黑料网
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- Email Address
- s.c.cotton@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438178
- Office Address
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Aberdeen Centre for Evaluation, Third floor, Health Sciences Building
Foresterhill Campus
Foresterhill
AB25 2ZD
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I joined HSRU in 2007 as a trial manager. I graduated from the 黑料网 with a BSc in Health Sciences in 1993, an MLitt in 1995, and a PhD in 2007. Prior to joining the Unit, I worked in the Department of Public Health at the 黑料网.
I am Head of Trial Management/Senior Trial Manager within CHaRT supporting the portfolio of trials.
Previously I was the Deputy Senior Trial Manager and supported a number of studies including RAACENO, EMPOWER and ELECTRIC (all now completed). I also worked as trial manager on a number of CHaRT trials, including ALLEGRO, BICS, TWICS, CLASS, NIAMI, FOCCUS, REFLUX and the Cysteamine in CF study.
I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.
Qualifications
- BSc Health Sciences1993 - 黑料网
- MLitt by research1994 - 黑料网
- PhD Public Health2008 - 黑料网
- Research
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Research Overview
Trial methodology & trial management
Research Areas
Current Research
I am the Senior Trial Manager within CHaRT supporting the portfolio of trials. I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.
I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.
Past Research
Since joining the Unit I have worked on a number of trials that have now been completed.
TWICS - a multicentre trial investigating the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease.
CLASS - a multicentre trial comparing foam sclerotherapy and endovenous laser ablation with conventional surgery in patients with varicose veins;
NIAMI - a phase II multicentre trial investigating whether an intravenous injection of sodium nitrite given immediately before the infarct related artery is opened reduces ischaemia reperfusion injury in patients with myocardial infarction;
FOCCUS - a pragmatic multi-centred randomised controlled trial of surgical HDU care versus HDU care delivered in an ICU and pre-operative fluid loading in high-risk patients undergoing major elective surgery
REFLUX - a multi-centre randomised trial comparing a policy of relatively early laparoscopic surgery with a continued best medical management policy for people with more severe gastro-oesophageal reflux disease.
The Cysteamine in CF study - a single-centre, single group open label study of oral cysteamine in patients with Cystic Fibrosis.
I also supported RAACENO, EMPOWER and ELECTRIC (all now completed) as senior trial manager.
- Teaching
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Teaching Responsibilities
I have supervised a number of undergraduate and Masters level research projects, including topics such as provision of information to potential participants, strategies to increase response rates, and outcome measures.
Non-course Teaching Responsibilities
Outwith the University, I am a faculty member on the Edinburgh Clinical Trial Management Course ().
- Publications
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Page 10 of 15 Results 91 to 100 of 141
Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform
Trials, vol. 16, 261Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
A normal colposcopy examination fails to provide psychological reassurance for women who have had low-grade abnormal cervical cytology
Cytopathology, vol. 26, no. 3, pp. 178-187Contributions to Journals: Articles- [ONLINE] DOI:
- [ONLINE]
Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial
Health Technology Assessment, vol. 19, no. 27, pp. 1-342Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Management of women with low grade cytology: how reassuring is a normal colposcopy examination?
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 122, no. 3, pp. 380-386Contributions to Journals: Articles- [ONLINE] DOI:
Normative data for the Hospital Anxiety and Depression Scale
Quality of Life Research, vol. 24, no. 2, pp. 391-398Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Measuring the psychosocial burden in women with low-grade abnormal cervical cytology in the TOMBOLA trial: psychometric properties of the Process and Outcome Specific Measure (POSM)
Health and Quality of Life Outcomes, vol. 12, 154Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial
British Journal of Surgery, vol. 101, no. 12, pp. 1532-1540Contributions to Journals: Articles- [ONLINE] DOI:
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A randomized trial comparing treatments for varicose veins
The New England Journal of Medicine, vol. 371, no. 13, pp. 1218-1227Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)
European Heart Journal, vol. 35, no. 19, pp. 1255-1262Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
The unintended consequences of cervical screening: distress in women undergoing cytologic surveillance
Journal of Lower Genital Tract Disease, vol. 18, no. 2, pp. 142-150Contributions to Journals: Articles- [ONLINE] DOI: