BEGIN:VCALENDAR VERSION:2.0 PRODID:-//ºÚÁÏÍø//NONSGML Events//EN METHOD:PUBLISH BEGIN:VTIMEZONE TZID:Europe/London BEGIN:DAYLIGHT TZOFFSETFROM:+0000 TZOFFSETTO:+0100 DTSTART:20210328T010000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=-1SU TZNAME:BST END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0100 TZOFFSETTO:+0000 DTSTART:20211031T020000 RRULE:FREQ=YEARLY;BYMONTH=10;BYDAY=-1SU TZNAME:GMT END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:24993 DTSTAMP:20261103T060601Z DTSTART;TZID=Europe/London:20261104T130000 DTEND;TZID=Europe/London:20261104T140000 LOCATION:MT 311 SUMMARY:Interdisciplinary Seminar- Dr. Izaak Neri DESCRIPTION:Speaker: Dr. Izaak Neri, King's College London Title: Amendable decisions in living systems Abstract: A distinct feature of living systems is their capacity to take decisions based on uncertain environmental signals. Examples span from the microscopic scale of cell differentiation guided by the concentration of a morphogen, to complex choices made by animals and humans. The current paradigm in decision theory assumes that decisions, once taken, cannot be revoked. However, living systems often amend their decisions if new evidence favours an alternative hypothesis. We will characterise the optimal strategy for such amendable decisions. We find that, unlike irrevocable decisions, optimal amendable decisions can be made in a finite average time with zero error probability. Our theory successfully predicts the outcome of a visual experiment involving human participants and the accuracy of cell-fate decisions in early development. We also present possible implementations of amendable decision-making by means of either biochemical reactions or transcription regulation. Visit /events/24993 for further details about this event. FBTYPE:BUSY-TENTATIVE X-MICROSOFT-CDO-BUSYSTATUS:TENTATIVE END:VEVENT END:VCALENDAR